The Laboratory for Bone and Muscle Cell Biology studies the regulation of differentiation and activity of cells of the musculoskeletal system.
We are interested in understanding regulation of the behaviour of bone, cartilage and muscle cells during development, regeneration and pathology, with particular emphasis on the roles of proteases and extracellular matrix.
- The role of protease-activated receptors in the pathophysiology of muscular dystrophy, periodontitis-associated bone loss and prostate cancer metastasis to bone
- Regulation of mesenchymal stem cell fate by protease-activated receptors
- The role of osteopontin in muscle regeneration
- Morphological diversity of chondrocytes in growth cartilage
- Bone health in dairy animals
- Bone microstructure and turnover in athletic horses (as part of the Equine Orthopaedic Research Group)
Research Group Contacts