The Laboratory for Bone and Muscle Cell Biology studies regulation of the behaviour of bone, cartilage and muscle cells during development, regeneration and pathology.
Areas of current interest include the role of protease-activated receptors in a variety of contexts such as muscle-bone interactions and periodontal disease, the role of the hypertrophic chondrocyte in bone growth, bone health in dairy cows and the structural basis for bone injury in racehorses.
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Our researchers and graduate research students
Professor Eleanor Mackie
Professor of Veterinary Preclinical Sciences
Eleanor Mackie is a veterinarian who undertakes research on basic aspects of musculoskeletal development and pathology. She has particular expertise in the study of bone and cartilage cell biology through the use of cell culture, animal models and a variety of methods for analysing tissue structure.
Dr Charles Pagel
Senior Lecturer in Agricultural Molecular Sciences
Charles Pagel is a biochemist and molecular biologist with 30 years’ experience investigating skeletal muscle and bone pathology, injury and regeneration. Dr Pagel has expertise in cell culture, transcriptomics, RT-PCR and the use of models of diseases of the musculoskeletal system to understand pathology and develop novel therapies.
Dr Reza Sanaei
Lecturer in Veterinary Biosciences
Reza Sanaei recently completed a PhD and has an research interest in biomaterials, bone biology and inflammatory bone disease. Reza has particular expertise in the use of bone imaging techniques and histomorphometry in the study of bone tissue.
Dr Babatunde Ayodele
Research Fellow in Musculoskeletal Biology
Tunde Ayodele is a veterinary graduate who undertakes research on limb injury in athletic horses. He brings expertise in molecular biology and structural analyses of bone and cartilage to the equine orthopaedic research at the University of Melbourne. He is broadly interested in the pathophysiology of musculoskeletal diseases.
Aisha Tarar is investigating the effects of milk yield, nutrient partitioning and lactation on bone health in dairy cattle in her PhD research.