Research in Veterinary Clinical Pharmacology

1) Antimicrobial resistance: what is the impact of pharmacokinetics on the rate of development of resistance to antimicrobial drugs? 2) Food Safety: What factors influen ce the persistence of drugs in food products of animal origin, with particular emphasis on bovine milk? 3) Drug Residues: How long do drugs persist and how long are they detectable in sample taken from racing and performance animals? 4) Ornamental fish: what factors affect the morbidity and mortality of ornamental fish during transportation? 5) Clinical Trials: we also conduct clinical trials for new drug products.

Group Contacts

Name: Dr Ted Whittem
Email: ted.whittem@unimelb.edu.au
Phone: 9731 2061
Campus: Werribee

Researchers

Ted Whittem, Simon Bailey, Cate Steele

RHD Students

Sarah Robson, Andrew Woodward

Events

ACVIM, EAVPT, ANZCVS Science Week

Next : Publications

Simpson C, Devi JL, Whittem T. 2013 Bioavailability of two thyroxine formulations after oral administration to healthy dogs. Australian Veterinary Journal 91(3):83-88.
Cudmore LA., Muurlink T., Whittem T., Bailey S.R. 2013 Effects of oral clenbuterol on the clinical and inflammatory response to endotoxaemia in the horse. Research in Veterinary Science, 94(3):682-686.
Kelers K, Devi JL, Anderson GA, Zahra P, Vine JH, Whittem T. 2013. The relative bioavailability of a new formulation of benazepril compared to the reference product. Australian Veterinary Journal, 91:312–319.
Metcalfe S, Hulands-Nave A, Bell M, Kidd C, Pasloske K, O’Hagan B, Perkins N and Whittem T. 2014. Multicentre, randomised clinical trial evaluating the efficacy and safety of alfaxalone administered to bitches for induction of anaesthesia prior to caesarean section. Australian Veterinary Journal 92(9);333-338.
Sullivan S. L., Whittem T., Morley P. S. and Hinchcliff K. W. 2015 A systematic review and meta-analysis of the efficacy of furosemide for exercise induced pulmonary haemorrhage in Thoroughbred and Standardbred racehorses. Equine Veterinary Journal 47(3):341-349.
Scheelings TF, Devi JL, Woodward A, Whittem T. 2015. Pharmacokinetics of enrofloxacin following oral and subcutaneous administration in the common ringtail possum (Pseudocheirus peregrinus). J. vet. Pharmacol. Therap . 38(5);482-487.
Bell, ET, Devi, JL, Chiu, S, Zahra, P, Whittem T. 2015. The pharmacokinetics of pimobendan enantiomers after oral and intravenous administration of racemate pimobendan formulations in healthy dogs. J. vet. Pharmacol. Therap. 39(1):54-61.
Woodward A. and Whittem T. Understanding intra-mammary beta-lactam pharmacokinetics using a physiologically-based model. Thirteenth International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Nantes, France. August 2015. Journal of Veterinary Pharmacology and Therapeutics, 38:suppl 1; p19.
Woodward A. and Whittem T. Population analysis of a physiologically based model of intra-mammary pirlimicin residues in bovine milk. Thirteenth International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Nantes, France. August 2015. Journal of Veterinary Pharmacology and Therapeutics, 38:suppl 1; p104.
Robson S., Whittem T., Marenda M. The impact of pharmacokinetics on emergence of in vitro bacterial resistance to cefovecin. Thirteenth International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT), Nantes, France. August 2015 Journal of Veterinary Pharmacology and Therapeutics, 38:suppl 1; p88.

Group contacts: Dr Ted Whittem